Any, for occasional use, just do it interactively. He says he wrote a program himself to automate it, but he could just have well used a Photoshop script (Action) in my opinion. I am almost certain that the original artist would have developed the style he uses with Photoshop. If you are in a University someone will have a copy of Photoshop (old versions are fine), but otherwise you will have to make do with what you can find. Next you need access to decent bitmap graphics application. The beauty of JMol is you can generate high resolution images which you can drag back into a JMol window and work on again later (as long as you haven’t edited them). Give a series of commands such as the following to get a spacefilling image (B) in colours other than CPK (you can specify the colours of the chains if you wish) and without the shiny light patches, which are fine for standard images, but will cause problems.Drag it into the JMol window when the molecule loads in wireframe mode as in (A), below.Get the PDB file I want to work with from the Protein Data Bank.Alternatively you can just find a web page with a JSMol window (such as a page used in my own teaching material) and use that with the Console available from the JSMol logo. You can either download the application and work with it as described in my answer to a previous question. The original 3D-graphics program used was RasMol, but as that only runs on Windows, hasn’t been updated for years, and has no viable web version, I would suggest using JMol/JSMol instead. I don’t actually consider these pictures either “gorgeous” or “cool” - they are not to my taste - and I’m not really sure that the question is about biology, but as it has resurfaced after almost 5 years I thought I’d give an answer which explained how one might create something similar, rather than how they were actually made. Although it may take a bit of tweaking (and possibly programming) I would surely give PyMOL and Bioblender a try. There are good tools around if you want to replicate that look. On the last page of each Molecule of the Month-"Exploring the Structure"-I always use RasMol, to give visitors an idea of the kinds of pictures that they can create themselves with off-the-shelf software. I like the way that this style simplifies the molecule, giving a feeling for the overall shape and form of the molecule, but at the same time you can still see all the individual atoms. I've been using this style of illustration-with flat colors and black outlines-for about 10 years now. Art Olson here at The Scripps Research Institute. Goodsell: Most of the pictures are created with a computer program that I developed back when I was doing postdoctoral work with Dr. PDB: How do you create the illustrations? Those (really cool) pictures are created by David Goodsell using custom-written software.
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